1,225 research outputs found

    Evaluation of star gyro torquing final report

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    Electrostatic gyroscope torquin

    Analysis and preliminary design of optical sensors for propulsion control

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    A fiber-optic sensor concept screening study was performed. Twenty sensor subsystems were identified and evaluated. Two concepts selected for further study were the Fabry-Perot fiber-optic temperature sensor and the pulse-width-modulated phosphorescent temperature sensor. Various designs suitable for a Fabry-Perot temperature sensor to be used as a remote fiber-optic transducer were investigated. As a result, a particular design was selected and constructed. Tests on this device show that spectral peaks are produced from visible white light, and the change in wavelength of the spectral peaks produced by a change in temperature is consistent with theory and is 36 nm/C for the first order peak. A literature search to determine a suitable phosphor for implementing the pulse-width-modulated fiber optic temperature sensor was conducted. This search indicated that such a device could be made to function for temperatures up to approximately 200 C. Materials like ZnCdS and ZnSe activated with copper will be particularly applicable to temperature sensing in the cryogenic to room temperature region. While this sensing concept is probably not applicable to jet engines, the simplicity and potential reliability make the concept highly desirable for other applications

    Regions of beta 2 and beta 4 responsible for differences between the steady state dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors

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    We constructed chimeras of the rat beta 2 and beta 4 neuronal nicotinic subunits to locate the regions that contribute to differences between the acetylcholine (ACh) dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 receptors. Expressed in Xenopus oocytes, the alpha 3 beta 2 receptor displays an EC50 for ACh approximately 20-fold less than the EC50 of the alpha 3 beta 4 receptor. The apparent Hill slope (n(app)) of alpha 3 beta 2 is near one whereas the alpha 3 beta 4 receptor displays an n(app) near two. Substitutions within the first 120 residues convert the EC50 for ACh from one wild-type value to the other. Exchanging just beta 2:104-120 for the corresponding region of beta 4 shifts the EC50 of ACh dose-response relationship in the expected direction but does not completely convert the EC50 of the dose- response relationship from one wild-type value to the other. However, substitutions in the beta 2:104-120 region do account for the relative sensitivity of the alpha 3 beta 2 receptor to cytisine, tetramethylammonium, and ACh. The expression of beta 4-like (strong) cooperativity requires an extensive region of beta 4 (beta 4:1-301). Relatively short beta 2 substitutions (beta 2:104-120) can reduce cooperativity to beta 2-like values. The results suggest that amino acids within the first 120 residues of beta 2 and the corresponding region of beta 4 contribute to an agonist binding site that bridges the alpha and beta subunits in neuronal nicotinic receptors

    Current Perspectives on Western Boreal Forest Life: Ethnographic and Ethnohistoric Research in Late Prehistoric and Historic Archaeology - A Preface

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    At the 1987 Society for American Archaeology Meetings in Toronto, several scholars gathered to present their most recent research using ethnographic and ethnohistoric information to study late prehistoric and historic Athabaskan archaeology in the western subarctic interior. ... The papers from this symposium make up the rest of this volume; this preface provides the reader with some background for better appreciating the papers that follow. The preface begins with a short historical summary of recent Athabaskan archaeology, including the use of ethnohistoric and ethnographic approaches. It continues with very brief summaries of the six papers as context for the subsequent comments, presented at the session by the symposium's two discussants, Polly McW. Quick and Donald W. Clark. Their comments touch on several important issues, including adaptation to environmental variability, the importance of explicit linkages between ethnographic information and archaeology, the value of oral history, the difficulties of projecting findings from recent historic sites back even to more distant historic sites, the promise and problems of interpreting social groupings from structural remains, the value of having northern researchers who live and work throughout the year in the North, and the need for better frameworks for linking ethnographic and ethnohistoric information with archaeology to permit some generalization. The preface closes with a discussion of future research directions and priorities. ...Key words: Alaska, archaeology, Athabaskans, boreal forest, Canada, ethnoarchaeology, ethnography, ethnology, ethnohistory, historic period, research priorities, Subarctic, symposiumMots clés: Alaska, archéologie, Athabaskans, forêt boréale, Canada, ethnoarchéologie, ethnographie, ethnologie, ethnohistoire, période historique, priorité dans la recherche, subarctique, symposiu

    Induction of Hexose-Phosphate Translocator Activity in Spinach Chloroplasts

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    Computer-Aided Design (CAD) Tools to Support the Human Factors Design Teams

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    The scope of this assessment was to develop a library of basic 1-Gravity (G) human posture and motion elements used to construct complex virtual simulations of ground processing and maintenance tasks for spaceflight vehicles, including launch vehicles, crewed spacecraft, robotic spacecraft, satellites, and other payloads. The report herein describes the task, its purpose, performance, findings, NASA Engineering and Safety Center (NESC) recommendations, and conclusions in the definition and assemblage of the postures and motions database (PMD)

    Photorespiration: metabolic pathways and their role in stress protection

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    Photorespiration results from the oxygenase reaction catalysed by ribulose-1,5-bisphosphate carboxylase/ oxygenase. In this reaction glycollate-2-phosphate is produced and subsequently metabolized in the photorespiratory pathway to form the Calvin cycle intermediate glycerate-3-phosphate. During this metabolic process, CO2 and NH3 are produced and ATP and reducing equivalents are consumed, thus making photorespiration a wasteful process. However, precisely because of this ine¤ciency, photorespiration could serve as an energy sink preventing the overreduction of the photosynthetic electron transport chain and photoinhibition, especially under stress conditions that lead to reduced rates of photosynthetic CO2 assimilation. Furthermore, photorespiration provides metabolites for other metabolic processes, e.g. glycine for the synthesis of glutathione, which is also involved in stress protection. In this review, we describe the use of photorespiratory mutants to study the control and regulation of photorespiratory pathways. In addition, we discuss the possible role of photorespiration under stress conditions, such as drought, high salt concentrations and high light intensities encountered by alpine plants

    Real-time selective sequencing using nanopore technology

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    The Oxford Nanopore Technologies MinION sequencer enables the selection of specific DNA molecules for sequencing by reversing the driving voltage across individual nanopores. To directly select molecules for sequencing, we used dynamic time warping to match reads to reference sequences. We demonstrate our open-source Read Until software in real-time selective sequencing of regions within small genomes, individual amplicon enrichment and normalization of an amplicon set
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